HLA-B27 is significantly associated with ankylosing spondylitis in Bangladeshi axSpA patients, and combined evaluation of clinical features and inflammatory markers may aid in early identification and management, particularly in resource-limited settings.
Combined stratification by sex and HLA-B27 status demonstrated that female HLA-B27-negative patients had the highest disease activity, functional impairment, and quality-of-life impairment among all subgroups.
E. Soliman, Magdy Zeheiry, Yasmine Abu Halawa et al.· BMC Musculoskeletal Disorder...· 0 citations
Comparisons of the clinical characteristics of enthesitis/ spondylitis-related juvenile idiopathic arthritis in Türkiye and India suggest that factors beyond HLA-B27, including broader genetic, environmental, and population-specific influences, may contribute to differences in disease expression.
R. Işgüder, Avinash Sharma, Zehra Kızıldağ et al.· Archives of Rheumatology· 0 citations
Background: Reactive arthritis (ReA) is an inflammatory rheumatic disease that belongs to the group of spondyloarthritis (SpA). Etiopathogenesis of ReA, as well as the majority of other SpA entities, is linked with the presence of HLA-B27. However, considerable uncertainty remains regarding the HLA-B27 positivity and i...
A divergent regulation of CD29 and CD49b integrins associated with HLA-B27 status in Iraqi AS patients is suggested and longitudinal validation is required to confirm their clinical utility as diagnostic or therapeutic targets.
Ahmed Ali Alshammari, M. Mohsin· Iranian Journal of Pathology· 0 citations
A meta-analysis of the results obtained from an independent two-sample MR analysis and a meta-analysis based on 3 independent MR estimates were consistent with the results obtained, and the results were consistent with the results the authors had previously obtained.
To compare the dynamics of spondyloarthritis activity with changes in total testosterone (TT) levels in men with ankylosing spondylitis (AS) and psoriatic arthritis (PsA), a comparative assessment of quantitative and qualitative indicators reflecting the clinical features of AS and PsA was conducted at baseline and ove...
T. Panevin, T. Korotaeva, T. Dubinina et al.· Rheumatology Science and Pra...· 0 citations
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