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Open access

MS4A8B regulates Orai1-dependent Ca²⁺ influx to control motile cilia function in human nasal epithelial cells

Alexander A. Simon Ray Z. Ma J. Rao Katherine Rozsypalek Zhongming Ma N. Adappa J. N. Palmer Yobouet Inès Kouakou R. J. Lee
Aug 2026 · bioRxiv · 0 citations · 107 references
Biology

TL;DR

Targeting this compartmentalized signaling pathway offers a novel therapeutic approach to restore or enhance mucociliary clearance in airway diseases.

DOI Semantic Scholar
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