Jul 2026· JOURNAL OF METALS, MATERIALS AND MINERALS· Vol 36, pp. e2657· 0 citations· 45 references
Abstract
Naturally produced Hydroxyapatite (HAP) yields beneficial attributes with regards to its biological functions including cell compatibility, proliferation and osteoinduction. This study synthesized HAP from oyster shells as a calcium source with multiple hydrothermal reaction times including 1 h, 6 h and 24 h at 150℃. A wet precipitated control sample was produced at room temperature. Characterization using FTIR, XRD, SEM-EDX and BET were conducted, followed by a degradation analysis. Bio-compatibility study of Oys-HAP was performed against Saos-2 osteoblast-like cells. The results showed nano scaled elongated and oval-shaped Oys-HAP particles with high crystallinity, beta-type carbonated, non-stoichiometric Ca/P ratio with a maximum surface area of 41.39 m2·g‒1. Furthermore, Oys-HAP samples were non-toxic and significantly enhanced Saos-2 cell proliferation by 65.6% compared to the negative control. These findings demonstrate the potential of oyster shell-derived Oys-HAP as a sustainable and effective biomaterial for biomedical applications.
The complementary effects of polymer reinforcement and dual-ion doping are demonstrated, suggesting great promise for Osteo-regenerative applications and Ce/Fe doped HAP sample possess superior anti-microbial efficiency against both gram (+)'ve and gram (-)'ve strains.
S. R, Kumaraguru S, Issathul Riswan M et al.· Journal of Biomaterials Scie...· 0 citations
The bamboo shell-derived HAp/Alg composite produced at pH 10 was a potential candidate for localized antibacterial drug delivery systems in biomedical applications and carried clindamycin efficiently carried on the composite matrix and released in a sustained manner.
Wulandari Wulandari, N. Jamarun, D. V. Wellia et al.· Baghdad Science Journal· 0 citations
Two types of hydroxyapatite were synthesized: pure hydroxyapatite and 5% magnesium-doped hydroxyapatite (based on weight percentage): pure hydroxyapatite and 5% magnesium-doped hydroxyapatite (based on weight percentage).
Subhasis Nath, S. K. Samanta, S. Debnath et al.· Journal of Polymer & Composi...· 0 citations
Using a plant-assisted sol–gel strategy, a hydroxyapatite–zinc oxide (HAp/ZnO) composite was produced from Padalarang calcite and lemon (Citrus limon L.) extract. The calcite supplied the calcium component, while constituents of the lemon extract promoted metal-ion complexation and helped control precursor stabilizatio...
Arie Hardian, Farah Fauziyah, Teguh Karya et al.· Journal of Mathematical and...· 0 citations
Bismuth(III)-doped 13–93 silicate bioactive glass powders were synthesized via a sol–gel route with Bi₂O₃ contents ranging from 0.1 to 5 wt% using two different precursors, BiCl₃ and Bi(NO₃)₃.5H2O. Structural characterization by X-ray diffraction and FTIR confirmed the predominantly amorphous nature of the glasses and...
A. M. Deliormanlı, H. Atmaca· Journal of Sol-Gel Science a...· 0 citations
Synthesis and characterization of improved bioactivity and cytocompatibility of hydroxyapatite (HAP) co‐functionalized with gelatin (G) and the amino acid leucine (L) or tyrosine (T) prepared through a hydrothermal process. Phase‐pure, nano HAP with a crystallite size of 15–18 nm and a minimum size of crystallites wa...
C. Elavarasi, J. V. Kumar, P. Saravanan et al.· Journal of Polymer Science· 1 citation
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