Oct 2026· Companion Publication of the 28th International Conference on Multimodal Interaction· 1 citation· 64 references
TL;DR
LUCID is presented, a modular conceptual reference architecture for non-diagnostic, patient-facing generative AI health coaching grounded in Therapeutic Patient Education (TPE) that separates curated knowledge, controlled health-context integration, analysis and personalization, response generation through an internal large language model (LLM) Gateway, safety, explainability, audit, and staged evaluation.
Abstract
Patient-facing generative AI is increasingly proposed for chronic self-management support, but trust-relevant properties such as source verification, safety boundaries, traceability, bias monitoring, and escalation are difficult to inspect when treated as emergent properties of a dialogue model. This paper presents LUCID, a modular conceptual reference architecture for non-diagnostic, patient-facing generative AI health coaching grounded in Therapeutic Patient Education (TPE). It separates curated knowledge, controlled health-context integration, analysis and personalization, response generation through an internal large language model (LLM) Gateway, safety, explainability, audit, and staged evaluation. The architecture mediates patient requests, preferences, symptom reports, wearable summaries, educational goals, source-linked explanations, and escalation notices through explicit responsibility boundaries. Six design requirements are derived from a related-work synthesis, and key decisions are documented through Architecture Decision Records (ADRs). A runtime walkthrough and staged evaluation plan show how the architecture can be tested from architecture readiness to human-centered feasibility. By making curated sources, released context fragments, competency targets, model and prompt versions, safety and release decisions, and escalation paths explicit, LUCID enables developers and evaluators to inspect and compare how individual patient-facing responses are produced.
A narrative and interpretative review reframes AI-generated patient instructions as a safety-critical informatics intervention rather than a language-simplification tool, and proposes a sevendomain safety framework covering factual accuracy, clinical completeness, actionability, medication clarity, escalation and safet...
A. Gwóźdź-Broczkowska· International Journal of Med...· 0 citations
Generative conversational AI can make health information easier to access, but its responses may still be unsupported, outdated, or poorly matched to the user. These risks are important in neurodevelopmental care, where occupational therapists and parents or caregivers require different levels of detail, language, and...
Pantelis Pergantis, Konstantinos Georgiou, N. Bardis et al.· Multimodal Technologies and...· 0 citations
Abstract Background High-quality problem-based learning (PBL) during internship is resource-intensive and difficult to scale without consistent facilitation. Although generative AI is increasingly used in health professions education, many applications remain on-demand answer tools that may not reproduce core PBL proce...
Zheng-Qi Zhao, Bai-Jing Wu, Shu-Yuan Tian et al.· JMIR Medical Education· 0 citations
Consumer AI health assistants increasingly connect medical records, patient reports, and wearable data across repeated interactions, but evaluation still focuses on isolated prompts and answers. This Perspective has two objectives: to define a journey-level evaluation and governance framework for record-linked patien...
Zonghai Yao, Hong Yu· npj Digital Medicine· 0 citations
G-CARL, a grounded, checklist-aligned reinforcement learning framework that combines multi-source retrieval for atomic claim verification with context-aware, instance-specific weighted checklists for response coverage, providing structured supervision for factuality, user-demand satisfaction, and expression quality wit...
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Cognitive Theatre is developed, a risk-aware conversational agent informed by cognitive behavioural therapy and implemented through a controller-mediated role-decomposed architecture that escalated all 50 extreme-risk inputs and received higher response-level ratings than two baselines in AI-based assessment and a two-...
Yiming Zhou, M. Honary, Amjad Fayoumi· Information Systems Frontier...· 0 citations
A new computational approach reveals how cells communicate to assemble into tissues. This could accelerate stem cell engineering, improve disease models, and inform therapies.
MIT News · Artificial Intelligence· news.mit.eduOct 15, 2026