The porous scaffolds of PLGA with a lower lactide/glycolide (LA/GA) molar ratio degraded faster due to their higher hydrophilicity than those of PLGA with a lower lactide/glycolide (LA/GA) molar ratio, demonstrating their potential for tissue engineering applications.
The scaffold showed the highest osteoinduction, and the scaffold with 530 ± 56 μm average pore diameter demonstrated the highest expression of osteodifferentiation marker genes in DPSCs, and the addition of nanoparticles into the polymer matrix led to the decrease in the expression of pro-inflammatory genes in macropha...
A. V. Yushkov, E. A. Kuvshinova, I. Bulygina et al.· Biomedical Materials· 0 citations
Carboxymethyl chitosan (CMCh) is a water-soluble chitosan derivative with excellent biocompatibility and biodegradability, making it a promising material for tissue engineering and controlled drug delivery. In this study, three-dimensional (3D) scaffolds based on a 50/50 CMCh/poly(N-vinylpyrrolidone) (PVP) mixture we...
M. Szulc, Sandra Lewandowska, T. Jędrzejewski et al.· Journal of Materials Science...· 0 citations
A polylactic acid/tea polyphenols polymer blend for coronary artery stents enhanced specimen hydrophilicity, biocompatibility, and stability by reinforcing the microstructure, crucial for long-term implants as it extends service life and minimizes complications from material fatigue.
Xu-Yu Sun· SAE technical paper series· 0 citations
The obtained results confirm the potential of PLA-based composites modified with hydroxyapatite and gentamicin as functional biodegradable materials for implant applications in regions with moderate mechanical loading, combining mechanical support, bioactivity, and local antimicrobial protection.
A. Khrustaleva, A. Yedrissov, D. Khrustalev et al.· Medicine and ecology· 1 citation
The in-vitro experiment revealed that the PCL-CQ composite electrospun scaffold showed better MG63 cell adhesion and growth compared to the control PCL scaffold and thus could be a potential scaffold material for bone defect applications.
P. Harikrishnan, Kayal Vizhi Kumaravel, Arayambath Balamani et al.· Trends in Biomaterials & Art...· 0 citations
The results showed that the composite scaffolds effectively improved the inflammatory microenvironment in the defect region, promoted macrophage polarization toward an anti-inflammatory phenotype, enhanced cellular osteogenic activity and mineralization, and facilitated new bone formation and tissue reconstruction.
Fang Tong, Ting-Ting Lu, Lu Tang et al.· Journal of materials chemist...· 0 citations
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