This review critically evaluates the design parameters of biopolymer delivery systems, focusing on the optimization of particle size and drug loading capacity and addresses key translational hurdles, including the biological limitations of active targeting and safety concerns like complement activation-related pseudoallergy.
In vitro and in vivo studies further demonstrated the potential of this nanoparticle system for controlled, targeted, and biocompatible delivery of anticancer agents.
Madhusudan Maity, Niranjan Panda, Subas C. Dinda et al.· Recent Patents on Nanotechno...· 0 citations
Evidence from recent studies demonstrates that MSNs significantly improve drug loading efficiency, enhance solubility and bioavailability, and reduce off-target toxicity, Consequently, MSNs represent a highly versatile and modifiable platform with considerable potential for addressing the limitations of conventional dr...
Ahmad Ainurofiq, Y. Ramadhana, Salma Aqilah Rachmadani et al.· Recent Advances in Drug Deli...· 0 citations
This review offers a comprehensive overview of research on herbal drug-loaded nanofibers and contributes a novel perspective with regulatory and clinical translational insights.
H. Polat, Yasin Turanlı, Nihat Kurt et al.· The Journal of the Science o...· 0 citations
A sophisticated blueprint for the next generation of nature-derived, “intelligent” biomaterials in cancer therapy is provided, providing a sophisticated blueprint for the next generation of nature-derived, “intelligent” biomaterials in cancer therapy.
Current trends of nanotechnology developments in the pharmaceutical market largely focus on the treatment of cancer, infectious diseases, central nervous system disorders and cardiovascular diseases, and lipid nanoparticle platforms are gaining relevance in current development pipelines.
Ronny Vargas, Fabiola Martos-Kikut, Noelia Martínez-Martínez et al.· ADMET and DMPK· 0 citations
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