Association of a near-MC4R gene variant (rs17782313) with hyperphagia among patients with severe obesity

Association of TCF7L2 Rs12255372 with Obesity and Adiposity Phenotypes Among Indonesian Medical Residents: A Cross-Sectional Genetic Association Study

Obesity is a complex phenotype arising from interactions between genetic susceptibility and environmental influences. This cross-sectional genetic association study examined the relationship between the TCF7L2 rs12255372 polymorphism and obesity and adiposity phenotypes among 152 Indonesian medical residents aged 25–45...

Association of APOA5 rs3135506 and CETP rs708272 Polymorphisms with Metabolic Syndrome in a Moroccan Population.

BACKGROUND Metabolic syndrome (MetS) is a multifactorial condition and a major public health concern due to its strong association with cardiovascular disease and type 2 diabetes. Genetic factors contribute to its development. This study aims to evaluate the association between polymorphisms in genes APOA5 and CETP and...

Association of FSHR rs6165 and ADIPOQ rs2241766 variants with polycystic ovary syndrome (PCOS) in Pakistani women: a two-locus genetic risk analysis

Polycystic ovary syndrome (PCOS) is a common multifactorial endocrine disorder with reproductive and metabolic manifestations. The contribution of variants involved in ovarian folliculogenesis and metabolic regulation remains incompletely understood in South Asian populations. This study investigated the association of...

Assessment of TCF7L2 Gene rs7903146 Polymorphism as Type 2 Diabetes Genetic Risk  Factor within Southern Iraqi Population

A strong association between the TCF7L2 rs7903146 polymorphism and type 2 diabetes mellitus susceptibility in the studied population is observed.

Associations of the single nucleotide polymorphism rs2228145 of the IL6R gene with features of the clinical course of hypertrophic cardiomyopathy

Introduction. The study of modifiable cardiometabolic risk factors (CMRFs) influencing the clinical phenotype of hypertrophic cardiomyopathy (HCM) is currently relevant. It is known that modifier genes can affect the course and progression of symptoms in HCM. At the same time, the analysis of associations between si...

Investigating the Association between Two Polymorphisms Rs2235749 and Rs910080 in the PDYN Gene and Susceptibility to Addiction