Malignant neoplasms of the reproductive system organs in women in the Kemerovo Region – Kuzbass: incidence, mortality, impact on life expectancy

Abstract

Introduction. The incidence of malignant neoplasms of the reproductive system organs is one of the indicators of women’s reproductive health – an important component of population reproduction.Materials and methods. A comparative analysis of the overall incidence rates of malignant neoplasms of the reproductive system organs and mortality from them in women in the Russian Federation and the Kemerovo Region – Kuzbass, as well as a graphical analysis of age-specific mortality rates from breast cancer, cervical cancer, uterine body cancer, and ovarian cancer were conducted. The contribution of mortality in certain age-related groups from cancer of the reproductive system organs of the leading locations to the differences in women’s life expectancy and the elimination reserves associated with its exclusion for increasing life expectancy was revealed.Results. In the Kemerovo Region – Kuzbass, as in the Russian Federation as a whole, tumors of the female reproductive system are leading in the structure of firstly diagnosed malignant neoplasms and related mortality. The most common oncopathology in women is breast cancer, the incidence of which has increased by 37.5% over the past 10 years in the Kemerovo Region. Reproductive system diseases account for 32% of the causes of death in women from oncopathology of all locations. In Kuzbass, cervical cancer causes the greatest irreversible losses among 30–49 years women, and breast cancer among women aged of 50 years and older. The elimination reserve for increasing life expectancy for women in Kuzbass, associated with the excluding of mortality from breast cancer, is 0.31 years, cervical cancer – 0.20 years, ovarian cancer – 0.11 years, and endometrial cancer – 0.10 years.Limitations. This study is limited by the territories selected for comparison (the Russian Federation and the Kemerovo Region – Kuzbass) and the current lack of availability of demographic data (age-specific mortality rates are available up to 2022, overall mortality rates from malignant neoplasms – up to 2023, overall incidence rates of malignant neoplasms – up to and including 2024).Conclusion. The obtained results are recommended for use in elaborating programs for the prevention and early detection of malignant neoplasms of the female reproductive system organs.Compliance with ethical standards. The study did not require the approval of a Bioethics Committee.Contribution: Baran O.I. – concept and design of the study, data analysis, writing the text; Babenko A.I. – concept and design of the study, editing the text. All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.Conflict of interest. The authors declare no conflict of interest.Funding. The study had no sponsorship.Received: May 14, 2026 / Revised: June 15, 2026 / Accepted: July 1, 2026 / Published: August 14, 2026