Open access

Integrative Proteomic Analysis Implicates Inhibition of Intracellular Protein Trafficking in Therapy-Induced Migrastasis in Prostate Cancer

Weining Chen Saadyeh Rashidi H. Law Fangfang Qiao Johnny W. Zigmond Katelyn L O'Neill Nicholas T. Woods C. Guda Raymond Bergan

Jul 2026 · bioRxiv · 0 citations · 80 references

Biology

TL;DR

KU2046-induced migrastasis appears to operate through spatial decoupling rather than structural degradation, providing a correlative framework to inhibit metastatic dissemination independent of direct cytotoxicity.

DOI Semantic Scholar

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