Identification of new protein-coding potential in Leishmania donovani using a proteogenomics approach

Soumi Chowdhury Shubhankar Pawar Karthick Vasudevan Nalini Mishra Mahendra D. Jamdhade Harsh Pawar

Aug 2026 · Current Microbiology · Vol 83 · 0 citations · 39 references

Medicine

TL;DR

It is demonstrated that proteogenomic integration significantly improves the accuracy of L. donovani genome annotation by resolving truncated gene models and uncovering hidden coding potential, which improve genome annotation and highlight previously unrecognised coding potential supported by peptide evidence in Leishmania donovani.

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