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CTPS1 promotes lung adenocarcinoma progression as a targetable vulnerability.

Hui Xie Cai-Xia Xu Bing-Han Zhou Fang Cheng Hong-Liang Xu Wen-Cheng Zhang Xue-Jun Shi Wenhao Shi Dong-Dong Zhan Guangshun Wang
Aug 2026 · British Journal of Cancer · 0 citations · 42 references
Medicine

TL;DR

Targeting CTPS1 with STP938, alone or in combination with osimertinib, represents a promising therapeutic strategy and supports CTPS1 as a targetable vulnerability in lung adenocarcinoma.

DOI PubMed Semantic Scholar
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