[Production and preliminary application of monoclonal antibodies against structural proteins of human parainfluenza virus type 3].

Characterization of a monoclonal antibody recognizing a conserved linear neutralizing epitope of pseudorabies virus gB protein

This work clarifies the molecular basis of PRV neutralization and identifies a conserved epitope, which upon further validation could serve as a diagnostic candidate and inform antiviral research.

Identi fi cation and characterization of new B cell epitopes on the nucleocapsid protein of bovine coronavirus using monoclonal antibodies

Mapping of three novel linear B-cell epitopes on the VP7 protein of epizootic hemorrhagic disease virus with monoclonal antibodies

Epizootic hemorrhagic disease virus (EHDV) is an important Orbivirus transmitted by culicoides midges. EHDV poses a significant threat to ruminant production worldwide. The VP7 protein is a highly conserved, group-specific antigen of EHDV, which serves as a key target for serological diagnosis. In this study, the recom...

Identification of a novel conserved B-cell epitope in the glycoprotein of rabies virus

This study identifies a novel, highly conserved with conservative substitutions linear B-cell epitope on the RABV glycoprotein, providing a precise molecular target for the rational design of next-generation epitope-based vaccines and specific diagnostic tools.

Monoclonal antibody 1B9 against the African swine fever virus viroporin pB169L: molecular characterization and epitope mapping

Introduction The African swine fever virus (ASFV) viroporin pB169L is a conserved membrane protein, but well-defined reagents for its detection and molecular characterization remain limited. Methods A soluble recombinant antigen comprising the non-transmembrane regions of pB169L was used to generate a mouse monoclonal...

High-affinity chicken scFv antibodies recognize recombinant VP1-CDEF' protein and native virions of feline calicivirus genotype II strain LZ2023

The generation of chicken-derived scFv antibodies targeting the FCV VP1-CDEF' region are reported, with high-affinity clones 2B2 and 2E1 are promising candidates for rapid diagnostic test development and warrant further evaluation.