Raw TMS and EMG data for: The Effect of Acoustically Structured Music on Motor Cortex Excitability and Sensorimotor Integration: A TMS Study

Abstract

This dataset contains subject-level (participant-averaged) transcranial magnetic stimulation (TMS) outcome measures from 20 healthy, non-musician adult participants in a within-subject crossover study examining the effects of unmodified (Control Music, CM) versus acoustically structured (Structured Music, SM) music on motor cortex excitability and sensorimotor integration. Each participant completed two experimental sessions (CM and SM, order counterbalanced by sequential enrollment number), separated by a minimum 24-hour washout period. Within each session, TMS measures were recorded at three time points: T0 (baseline, before music onset), T1 (during music listening), and T2 (post-music). The workbook is organized into six sheets, one per Session × Time combination (Kt0, Kt1, Kt2 = Control session at T0/T1/T2; Yt0, Yt1, Yt2 = Structured session at T0/T1/T2). Each sheet contains one row per participant (identified by anonymized numeric ID) and the following subject-level averaged values: Short-latency afferent inhibition (SAI) at 20, 22, and 24 ms interstimulus intervals, expressed as percentage inhibition/facilitation Test-alone (unconditioned) motor evoked potential (MEP) amplitude (mV), which also served as the study's global MEP amplitude measure Cortical silent period (CSP) duration (ms) Values represent within-participant averages across trials (20 trials per SAI/test-alone condition; 10 recordings per CSP measurement), consistent with the methods reported in the associated manuscript. Data were acquired using a Duomag MP stimulator with a 70 mm figure-eight coil (Deymed, DuoMAG) and recorded via Cambridge Electronic Design (CED) 1401 hardware with Signal 8.0 software. Peripheral electrical stimulation for the SAI paradigm was delivered to the median nerve at the wrist. These data support the linear mixed-effects and generalized linear mixed model analyses reported in the associated manuscript. Participant identifiers have been anonymized (numeric ID only); no directly identifying information is included. Keywords: transcranial magnetic stimulation; motor evoked potential; cortical silent period; short-latency afferent inhibition; music; sensorimotor integration