The findings demonstrate that the anti-inflammatory and hyaluronan-producing properties of XsE may contribute to the regulation of epidermal inflammatory responses and skin barrier-associated functions.
This study highlights WSCE as a potential anti-dermatitis agent, suppressing pro-inflammatory mediators in T+I-stimulated keratinocytes via MAPK and NF-κB regulation and position WSCE as a promising candidate for ISD management.
Uveitis is a sight-threatening inflammatory ocular disorder. Benzyl isothiocyanate (BITC) exhibits potent anti-inflammatory pharmacological activity. This research was designed to explore the therapeutic mechanism of BITC in acute uveitis (AU). We established a mouse model of endotoxin-induced uveitis (EIU) to evaluate...
Wendan Yi, Si-Jie Liu, Hai-Yue Wang et al.· International Immunopharmaco...· 0 citations
The ethanolic extract of SMS attenuated LPS-induced inflammatory and oxidative stress responses in RAW 264.7 macrophages, suggesting effects may be associated with the suppression of inflammatory mediator production, reduction in the cellular oxidative stress burden and modulation of proteins involved in cellular stres...
Nianshou Zhao, Hongya Li, Peng Ji et al.· Antioxidants· 0 citations
This study investigated the immunostimulatory activity and underlying mechanism of Ribes fasciculatum leaf water extract in RAW264.7 macrophages. Among extracts prepared using water or ethanol-containing solvents, only the water extract induced NO production. Further evaluation of extraction temperature and time identi...
So Jung Park, Jeong Won Choi, H. Choi et al.· Journal of Microbiology and...· 0 citations
Results show apigetrin not only improves the skin barrier of the epidermis but also exhibits excellent anti-inflammatory effects in a dermis cell model.
Jung Hyun Lee, Min Ji Kim, H. Hwang· Advances in Traditional Medi...· 0 citations
BACKGROUND
Persistent oxidative stress disrupts intrahepatic immune homeostasis, leading to cytokine dysregulation and fibrogenic progression in the liver. This study investigated the immunomodulatory and antifibrotic effects of methanolic extracts of Amaranthus spinosus (leaf, stem, and root) in a thioacetamide (TAA)-...
Sanchari Bhattacharyya, Uma Dutta, Anik Pramanik et al.· Tissue & Cell· 0 citations
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