Skip to content

Xanthium strumarium L. extract attenuates TNF-α/IFN-γ- stimulated inflammation and promotes hyaluronan production on HaCaT keratinocytes

Aug 2026 · Molecular Biology Reports · Vol 53 · 0 citations · 37 references
Medicine

TL;DR

The findings demonstrate that the anti-inflammatory and hyaluronan-producing properties of XsE may contribute to the regulation of epidermal inflammatory responses and skin barrier-associated functions.

View source

Similar papers

Open access Jul 2026

Bioactive dicaffeoylquinic acid-enriched callus extract of Weigela subsessilis inhibits TNF-α/IFN-γ-induced keratinocyte inflammation via MAPK and NF-κB pathways

This study highlights WSCE as a potential anti-dermatitis agent, suppressing pro-inflammatory mediators in T+I-stimulated keratinocytes via MAPK and NF-κB regulation and position WSCE as a promising candidate for ISD management.

Genevieve Tonog, Hyeonjun Yu, Derrick Kakooza et al. · 0 citations
Open access Aug 2026

Benzyl isothiocyanate alleviates endotoxin-induced uveitis in association with LOX-1 downregulation to modulate JAK2-STAT3 signaling, endoplasmic reticulum stress and apoptosis.

Uveitis is a sight-threatening inflammatory ocular disorder. Benzyl isothiocyanate (BITC) exhibits potent anti-inflammatory pharmacological activity. This research was designed to explore the therapeutic mechanism of BITC in acute uveitis (AU). We established a mouse model of endotoxin-induced uveitis (EIU) to evaluate...

Wendan Yi, Si-Jie Liu, Hai-Yue Wang et al. · 0 citations
Open access Aug 2026

Ethanolic Extract of Sophora moorcroftiana Seeds Attenuates LPS-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages via Modulation of the p62/Keap1/Nrf2 Signaling Pathway

The ethanolic extract of SMS attenuated LPS-induced inflammatory and oxidative stress responses in RAW 264.7 macrophages, suggesting effects may be associated with the suppression of inflammatory mediator production, reduction in the cellular oxidative stress burden and modulation of proteins involved in cellular stres...

Nianshou Zhao, Hongya Li, Peng Ji et al. · 0 citations
Sep 2026

Ribes fasciculatum Leaf Water Extract Enhances Macrophage Immune Responses via TLR4-Mediated JNK and NF-κB Activation in RAW264.7 Cells

This study investigated the immunostimulatory activity and underlying mechanism of Ribes fasciculatum leaf water extract in RAW264.7 macrophages. Among extracts prepared using water or ethanol-containing solvents, only the water extract induced NO production. Further evaluation of extraction temperature and time identi...

So Jung Park, Jeong Won Choi, H. Choi et al. · 0 citations
Jul 2026

Methanolic extracts of Amaranthus spinosus (Linn.) mitigate TAA-Induced hepatic fibrosis through modulation of inflammatory cytokines and profibrotic signalling.

BACKGROUND Persistent oxidative stress disrupts intrahepatic immune homeostasis, leading to cytokine dysregulation and fibrogenic progression in the liver. This study investigated the immunomodulatory and antifibrotic effects of methanolic extracts of Amaranthus spinosus (leaf, stem, and root) in a thioacetamide (TAA)-...

Sanchari Bhattacharyya, Uma Dutta, Anik Pramanik et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.