We show that continuous bitstream diffusion (CoBit), originally developed for language modeling, provides a unified framework for joint and conditional multimodal generation using the same training and sampling protocol. Across image-text, speech-text and protein sequence-structure modeling, models are trained separately from scratch, but each uses a single input projection, transformer backbone, bitwise prediction head and binary score-matching objective shared across its modalities. Within each setting, a single checkpoint supports joint generation and the conditional directions included in training by changing which parts of the bitstream are observed. We first validate the approach on MNIST-Sum, a controlled image-text task pairing raw binary images with equations encoded as text, achieving near-perfect conditional accuracy and high joint consistency without learned tokenizers. We then apply the same protocol at larger scale to speech-text and protein sequence-structure modeling. Trained without text pretraining, a single speech-text model performs speech synthesis, recognition, continuation, and unconditional co-generation. Jointly generated speech and text achieve 3.5% word error rate between the generated text and automatic transcriptions of the generated speech. In protein modeling, a single CoBit checkpoint supports forward folding, inverse folding, and joint sequence-structure generation. For jointly generated proteins spanning 100-500 residues, computational refolding of CoBit's sequences yields structures that agree with the generated backbones at a mean self-consistency TM-score of 0.911. Together, these results show that CoBit provides a common generative framework for substantially different modalities and forms of cross-modal dependence, without introducing a domain-specific objective or sampling procedure.
This publication proposes a definition and a classification of agile software development approaches and analyses ten software development methods that can be characterized as being "agile" against the defined criterion.
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Consequences of happiness and unhappiness that are beneficial and detrimental for developers' mental well-being, the software development process, and the produced artifacts are found.
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The Mobile-D approach is briefly outlined here and the experiences gained from four case studies are discussed, which helped develop an agile development approach for mobile application development.
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GAOKAO-Bench is introduced, an intuitive benchmark that employs questions from the Chinese GAOKAO examination as test samples, including both subjective and objective questions that contribute a robust evaluation benchmark for future large language models and offers valuable insights into the advantages and limitations...
Xiaotian Zhang, Chun-yan Li, Yi Zong et al.· arXiv.org· 216 citations· ⚡17
This state-of-practice investigation was performed using a literature review followed by a multiple-case study approach and presents how inconsistency between managerial strategies and execution can lead to failure by means of a behavioral framework.
Carmine Giardino, Xiaofeng Wang, P. Abrahamsson· International Conference on...· 175 citations· ⚡19
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MIT News · Artificial Intelligence· news.mit.eduAug 27, 2026
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.