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#artificial intelligence Preprint Open access

LingLanMedBench: A Unified Benchmark for Evaluating Large Language Models in Traditional Chinese Medicine

Rui Hua Yu Wei Zixin Shu Kai Chang Dengying Yan Jianan Xia Hui Zhu Xiaodong Li Dongmei Jia Zhuye Gao Yanyan Meng Haibin Yu Fei Dong Kan Ding Runshun Zhang Jian Yu Jiansheng Li Baoyan Liu Wenjia Wang Xuezhong Zhou
Oct 2026
Artificial Intelligence

Abstract

Reliable evaluation of large language models in traditional Chinese medicine remains limited because existing benchmarks mainly focus on examination-style question answering or isolated generative tasks. We developed LingLanMedBench, a unified benchmark comprising 25,620 expert-verified items across 13 subtasks and five domains, covering knowledge, language understanding, information extraction, and diagnostic-therapeutic decision-making. LingLanMedBench standardizes task formats and evaluation metrics and further incorporates synonym-tolerant clinical-label matching, empirically derived hard subsets, and decision-recognition reformulations of open-ended clinical tasks. Fourteen open-source and proprietary models were evaluated under a standardized zero-shot protocol. Performance varied substantially across domains, model families, task formulations, and difficulty levels. The leading overall score decreased from 51.1 on the full benchmark to 31.9 on the hard subsets. Prescription performance also differed markedly between open-ended generation, with F1 scores of 32.7 and 20.3, and decision recognition, with accuracies of 90.6 and 56.8 on the full and hard subsets, respectively. These findings reveal a substantial gap between knowledge-oriented performance and clinically faithful reasoning. LingLanMedBench provides a standardized and reproducible framework for characterizing current capabilities, identifying systematic limitations, and tracking meaningful progress in large language models for traditional Chinese medicine.

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