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Pro-Regenerative Machinery Involved in Regeneration-Approach-Based Anti-Ageing Strategy

Oct 2026 · Regeneration
Genetics, Aging, and Longevity in Model Organisms

Abstract

A complex biological mechanism, ageing is the gradual decline in tissue utilisation and restoration of functions. Recent studies show that ageing can be slowed down or reversed with the application of pro-regenerative machinery. Of critical healing processes evaluated in this study, immune modulation, stem cell and cellular reprogramming, as well as mitochondrial activation, were assessed as potential anti-ageing strategies. The current state of affairs in enhancing medicine, anticipated treatment modalities, and prospective directions for achieving greater life expectancy through medicinal regeneration were discussed. In order to counter restoration of cellular imbalance and promote active ageing, we target advanced treatment options like stem cell therapy, senolytics, metabolic modulators, and comprehensive gene editing strategies. While these methods seem promising, they still raise concerns about safety, efficacy, and practicality for widespread clinical use. In order to summarise and deliver the less optimistic potential of anti-ageing therapies, further research should be directed towards the refinement of regenerative manipulations.

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