Oct 2026· Immunity, Inflammation and Disease· Vol 14· 0 citations· 48 references
Medicine
TL;DR
Cumulative evidence supports the role of the intestinal epithelial barrier, immune system and gut microbiota in the progression of Crohn's disease.
Abstract
Crohn's disease (CD) is a multifactorial inflammatory bowel disease (IBD) characterized by impaired epithelial barrier integrity, excessive immune hyperactivation, and gut microbiota perturbations. Cumulative evidence supports the role of the intestinal epithelial barrier, immune system and gut microbiota in the progression of CD.
The gut–skin axis links intestinal microbial activity with inflammatory skin disease, yet findings across atopic dermatitis, acne vulgaris, and psoriasis remain inconsistent. This review examines how disease biology and host context shape microbiome‐related effects and responses to probiotics.
Pranvi Sharma, Tanaka Nhokwara, Jaswinder Singh et al.· Immunity, Inflammation and D...· 0 citations
The gut microbiota has long been recognized as a critical "hidden organ" that interacts dynamically with host animals, playing irreplaceable roles in regulating nutrient metabolism, shaping immune function, and maintaining systemic health [...].
This study aimed to delineate fecal microbiome and metabolomic signatures in RA and identify biomarkers associated with disease activity and identify biomarkers associated with disease activity.
Jing Liang, Xiang-Yu Wei, Chen Shang et al.· International Journal of Rhe...· 0 citations
Inflammatory Bowel Disease (IBD) is a chronic, relapsing inflammatory disorder of the
gastrointestinal tract that arises from complex interactions among genetic susceptibility, environmental
factors, immune dysregulation, and alterations in the gut microbiota. Increasing evidence
has established gut microbial dysbi...
Hassham Anwar, Shashank Soni· Letters in Functional Foods· 0 citations
A growing body of epidemiological evidence indicates that patients with IBD carry an elevated risk of cardiovascular events, including coronary artery disease, stroke, heart failure (HF), venous thromboembolism (VTE)
Kacper Byczek, Martyna Dutka, Mikołaj Asztabski et al.· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.