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Review Open access Sep 2026

INFLAMMATORY BOWEL DISEASES AND THE RISK OF CARDIOVASCULAR EVENTS — A LITERATURE REVIEW

Inflammatory bowel disease (IBD) — ulcerative colitis (UC) and Crohn's disease (CD) — comprises chronic, immune-mediated disorders of the gastrointestinal tract whose pathophysiological impact extends beyond the intestinal mucosa. A growing body of epidemiological evidence, including large-scale meta-analyses, indicate...

Kacper Byczek, Martyna Dutka, Mikołaj Asztabski et al. · 0 citations
Review Open access Oct 2026

Inflammatory bowel disease and the heart: how trained immunity shapes cardiovascular outcomes

Inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, is a chronic relapsing intestinal inflammatory disorder. Cardiovascular disease (CVD) is a leading cause of death in patients with IBD, with elevated risks of myocardial infarction, heart failure, stroke, and venous thromboembolism tha...

Shuang-Hua Liang, Long Han · 0 citations
Review Open access Sep 2026

Inflammatory Bowel Disease: From Multifactorial and Metabolic Pathogenesis to Systemic Disease and Precision Medicine

Introduction: Inflammatory bowel disease (IBD) is an umbrella term encompassing two major chronic immune-mediated disorders, Crohn’s disease (CD) and ulcerative colitis (UC). Its pathogenesis reflects complex interactions among genetic, microbial, metabolic, environmental, and immune factors. Growing evidence supports...

V. S. D. de Oliveira, Elizangela dos Anjos Silva, S. Gomes · 0 citations
Review Open access Oct 2026

Pediatric inflammatory bowel disease: a review of current research

Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis, is a growing global health challenge, with approximately 25% of cases diagnosed before the age of 20. These chronic immune- mediated disorders result from complex interactions between genetic predisposition, environmental triggers...

Alina Mykhalevych, Julia Grygorowicz, Monika Sas-Wyżykowska et al. · 0 citations

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