Sep 2026
Neoadjuvant chemoimmunotherapy improves outcomes in resectable non-small cell lung cancer, yet pathologic response incompletely predicts durability of benefit. Spatial profiling using resected tumors and lymph nodes revealed distinct immune subtypes and identified a gene signature associated with improved outcomes, pro...
V. Wang, Natalie M. Ward, J. Kratz
· Clinical Cancer Research · 0 citations
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Sep 2026
Molecular residual disease (MRD), detected via circulating tumor DNA (ctDNA) after curative-intent surgery, identifies resectable solid tumor patients at high recurrence risk, thereby enabling enriched trials with larger effect sizes and smaller samples. Yet enrichment narrows the eligible population and thus challenge...
S. Kobayashi, T. Hashimoto, H. Bando et al.
· Cancer Cell · 0 citations
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Open access
Oct 2026
There was an error in the original publication [...].
J. Kühn, W. Schmid, Sandrina Körner et al.
· Cancers · 0 citations
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Open access
Sep 2026
This study evaluated multiple CDKN2A/B FISH cutoffs and assessed the diagnostic and prognostic performance of MTAP and p16 IHC.
A. Ricci, Filippo Nozzoli, Alessandro Biale et al.
· Neuropathology and Applied N... · 0 citations
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Open access
Sep 2026
It is suggested that baseline and early on-treatment multigene ctDNA carries prognostic information in advanced PDAC, although superiority over KRAS or CA19-9 was not established.
Gi-Ye-On Lee, J. W. Chun, Dong-eun Lee et al.
· International Journal of Mol... · 0 citations
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Editorial
Sep 2026
Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing...
T. Taha, Ossian Longoria, J. de Bono
· European Urology · 0 citations
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