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Vinpocetine attenuates myocardial ischemia/reperfusion injury in mice by suppressing oxidative stress, inflammation, and apoptosis.

Tian-Chen Xia Yichen Qian YiLong Jiang Qiang Zhang Jiahao Pan Hui Xiong Jia-Xin Zhang Taotao Yan Qi Li Shenjie Zhang Q. You
Aug 2026 · Naunyn-Schmiedeberg's Archives of Pharmacology · 0 citations · 51 references
Medicine

TL;DR

Observations in the current work imply that heart-protective benefits conferred by VIN occur to a substantial degree via blockade of NLRP3 inflammasome activity, in which suppression of the NLRP3 inflammasome may constitute one key pathway accounting for such beneficial outcomes.

DOI PubMed Semantic Scholar
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