Is the specific treatment of HLH mandatory; and which option to choose between corticosteroids and intravenous immunoglobulins in association with antibiotherapy?
Abstract
Unlike haemophagocytic lymphohistiocytosis (HLH) induced by tuberculosis or rickettsial disease, there is no consensus for the treatment of HLH secondary to typhoid fever (Salmonella Typhi). After a short illustrative example, we searched among the previously described cases of HLH secondary to typhoid fever to determine: (i) Is the specific treatment of HLH mandatory; and (ii) which option to choose between corticosteroids and intravenous immunoglobulins in association with antibiotherapy?
Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory response syndrome. Common infectious triggers include Epstein Barr virus, cytomegalovirus, bacteria, and other pathogens. We report a case of HLH caused by human herpesvirus-6 (HHV-6) in a pediatric patient. Based on the HLH-2004 diagnostic criteria, the...
Li-Hong Gao, Yang Wen· Journal of Pediatric Infecti...· 0 citations
Melioidosis, caused by Burkholderia pseudomallei, is endemic in parts of South India and can be difficult to diagnosedue to its varied clinical presentations. Lack of awareness and persistent fever despite treatment may further delaydiagnosis. We report the case of a 47-year-old man with diabetes mellitus and a history...
Darshan H, S. Narayan, Prashanth M. R.· Indian Journal of Case Repor...· 0 citations
This report underscores the diagnostic difficulty, rapid deterioration and high mortality risk when HLH coexists with opportunistic infections when HLH coexists with opportunistic infections.
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Abstract Neoehrlichia mikurensis is an emerging tick-borne pathogen that is increasingly reported and can cause fever of unknown origin in immunocompromised individuals. We report a case of neoehrlichiosis occurring after B-cell-depleting treatment. Despite the availability of effective and inexpensive treatment, patie...
R. Martischang, C. Buclin, R. Bonnet et al.· Access Microbiology· 0 citations
Primary tuberculosis (TB) are usually pulmonary, an increase in extra-pulmonary TB as cervical lymphadenitis has been reported frequently. Phlyctenular Keratoconjunctivitis (PKC) and Erythema nodosum (EN) are manifestations of an immunological response to tuberculosis. EN and PKC may rarely be associated with this, bu...
Mahmuda Hassan, Masuma Khan, A. Mukti et al.· The Journal of Ad-din Women'...· 0 citations
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