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Nitrogen-doped carbon nanodots as a biocompatible FRET donor for caspase-3 detection and chemotherapy response evaluation in osteosarcoma cell lysates

Aug 2026 · Analytical Sciences · Vol 42, pp. 993 - 1008 · 0 citations · 42 references
Medicine

TL;DR

An “off–on” fluorescent nanosensor based on nitrogen-doped carbon nanodots (N-CNDs) for the sensitive and selective detection of caspase-3 activity, a key apoptosis executor, exhibits high sensitivity, excellent selectivity, and robust performance in complex biological media.

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