Aug 2026· Analytical Sciences· Vol 42, pp. 993 - 1008· 0 citations· 42 references
Medicine
TL;DR
An “off–on” fluorescent nanosensor based on nitrogen-doped carbon nanodots (N-CNDs) for the sensitive and selective detection of caspase-3 activity, a key apoptosis executor, exhibits high sensitivity, excellent selectivity, and robust performance in complex biological media.
A multifunctional nanodrug system, CuV/DTPA@Catalase/99mTc-5FU, engineered for enhanced anticancer efficacy and imaging that can overcome limitations of conventional chemotherapy by regulating the NF-κB pathway and enabling precise drug delivery is presented.
Iqra Iqbal, Ummama Saeed, B. Fatima et al.· International Journal of Bio...· 0 citations
A ratiometric fluorescence nanosensor using dual-emission CdTe quantum dots (R-QDs) for sensitive detection of APE1, a DNA repair enzyme and cancer biomarker, successfully detected APE1 in breast cancer cell lysates with good linearity and recovery rates.
As a key tumor suppressor gene, the mutation and abnormal expression of p53 are closely correlated with tumor occurrence and progression, making p53 an important biomarker for early tumor diagnosis. Herein, a novel fluorescent biosensor based on a Cas12a/alkaline phosphatase (ALP) cascade signal amplification strategy...
Xiao-Ya Wu, Qiu-Hang Chen, Jian-Jun Zheng et al.· In Analysis· 0 citations
This study presents the synthesis and evaluation of a novel multifunctional bimetallic nanocomposite comprising gold (Au) and cadmium (Cd) nanoclusters (NCs) embedded within bovine serum albumin (BSA) nanoparticles for advanced cancer theranostics. The structural and optical properties of the Au-Cd/BSA nanocomposites w...
Shayan Shahsavari, Mohammad Behnam Rad, Fatemeh Sadat Mahdavi et al.· Scientific Reports· 0 citations
The developed carbon-based nanoplatform showed significant tumor specificity and inhibition, making it a significant approach for a potential multifunctional treatment strategy for cancer.
Z. Sarkar, Varshini Are, Bhavesha Chanchlani et al.· ACS Applied Nano Materials· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.