Aug 2026· Clinical reviews in allergy and immunology· Vol 69· 0 citations· 383 references
Medicine
TL;DR
Evidence for potential synergy among probiotic combinations, contrast probiotic-based interventions with conventional immunosuppressive regimens in terms of their putative advantages and limitations, and examine the prospects for precision probiotic strategies alongside current challenges are discussed.
The gut microbiota is a critical regulator of systemic immune homeostasis; accumulating evidence implicates specific commensal bacteria, termed “pathobionts,” in autoimmune disease pathogenesis. However, the definition of pathobionts remains context-dependent, as their effects are influenced by host genetics and host–m...
Kentaro Kuzuya, Y. Maeda, Kenji Funakoshi et al.· Frontiers in Immunology· 0 citations
This review consolidates current insights on Weissella SP, an emerging and underexplored genus of Lactic acid bacteria with unique metabolic and immunomodulatory properties, positioning Weissella as an underexplored yet promising component of next-generation probiotic blends for IBD therapeutics.
Hima Sebastian, B. Babu, K. Gayathri et al.· Antonie van Leeuwenhoek· 0 citations
Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease that imposes a substantial lifelong burden on patients, particularly as it commonly develops during adolescence or early adulthood. Despite major advances in pharmacological management, including the introduction of biologic agents and small-mole...
Jana Štofilová, Veronika Benetinová, I. Bertková et al.· Frontiers in Microbiology· 0 citations
This review establishes a theoretical foundation for the preclinical research of CA, highlights its translational potential as a novel natural immunomodulator for the management of ADs, and offers insights for future drug development and rational clinical application of this compound.
Current evidence on interactions between the microbiome and therapies for allergic diseases, focusing on antihistamines, corticosteroids, leukotriene receptor antagonists, and biologic agents is summarized.
Miljana Poparić, Borko Milanovic, David Strilić et al.· Microbiology Research· 0 citations
Ulcerative colitis is a chronic inflammatory disease of the large intestine, involving flare-ups and remissions. Its exact causes are unclear, but genetic susceptibility, immune dysregulation and environmental influences promote development. Conventional treatments have improved management, but some patients only respo...
C. Caputo, Azzurra Chiara De Maio, Angela Lombardi et al.· Biomedicine & pharmacotherap...· 0 citations
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