2026· Advances in Experimental Medicine and Biology· Vol 1512, pp.
333-354
· 0 citations
Medicine
TL;DR
A unified multiscale perspective linking electric field distribution, pore formation, and molecular transport is presented to guide the design and optimization of electroporation devices to support the rational development of next-generation therapeutic, diagnostic, and cell handling tools.
A continuous pore formation model adapted for the 8-pulse ESOPE protocol is proposed that provides a quantitative framework for optimising electrochemotherapy parameters in small-cell systems by accounting for cumulative transport and cellular scale variability.
Jéssica Rodrigues, R. Guedert, J. Anselmo et al.· Bioelectrochemistry· 0 citations
This reagent-minimal, modular NEP platform provided a high-efficiency, low-toxicity route for saRNA delivery into hard-to-transfect immune cells, offering a versatile engineering framework for DC-based cancer immunotherapy, RNA vaccine development, and broader cell gene-modification applications.
Bowen Zhang, Yi-Jing Cai, Caiguanxi Deng et al.· Microsystems & Nanoengineeri...· 0 citations
The results suggest that piezoelectric ultrasound-assisted microjetting offers a clogging-resistant strategy with potential for future scale-up in carrier-free intracellular delivery of biomacromolecules and nanomaterials.
Jian-Feng Chen, Ke Li, Yi-Chuan Di et al.· Lab on a Chip· 0 citations
Critical deficiencies are highlighted, the sharp boundary between reversible and irreversible electroporation is explored, and calls for better reporting, standardized nomenclature, and interdisciplinary collaboration to elevate electroporation from an empirical to a universally predictive, robust science.
Electrokinetic transport in nanoscale systems has garnered significant interest because of its potential applications in desalination, molecular separation, and ion-selective devices. In particular, electroosmotic flow (EOF) through selective membranes offers a promising mechanism for voltage-driven reverse osmosis....
D. A. Aldave, Soufiane Abdelghani-Idrissi, A. Siria· Journal of Physical Chemistr...· 0 citations
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