Skip to content

Similar papers

Open access Aug 2026

A genetic screen unveils key molecular steps in the polymerization cycle of the bacterial actin-like MreB

Key mechanistic steps coordinating ATP-driven MreB polymerization and turnover are established and provide a basis for a complete MreB assembly–disassembly cycle and for further elucidating how MreB dynamics contribute to cell-wall organization.

Alba de San Eustaquio-Campillo, C. Cornilleau, Sana Afensiss et al. · 0 citations
Open access Aug 2026

Actin filament assembly driven by distributive polymerases clustered on membrane surfaces.

It is concluded that surface-mediated polymerization can outpace solution-mediated elongation, even at high actin concentrations (>100 μM); the finite time required for profilin dissociation decreases the advantage conferred by surface-associated polymerases, but only in the absence of force.

R. D. Mullins, Jane Kondev, Kristen Skruber · 0 citations
Review Open access Sep 2026

Coordinated Arp2/3-mediated actin branching and myosin-dependent force generation in membrane–cytoskeleton remodeling

The Arp2/3 (Actin-Related Protein 2/3) complex nucleates branched actin networks, while myosin motors generate force and reorganize actin through ATP-dependent motor activity. Their coordination is central to membrane remodeling, but the underlying mechanisms differ substantially among cellular processes and organisms....

Chun-Zhen Jiang, Yi-Fan Li, Jiang-Hong He · 0 citations
Open access Jul 2026

Multiscale Conformational Dynamics of DNA Holliday Junctions Modulated by Ion Concentration: Insights from Fluorescence Correlation Spectroscopy and Time-Resolved Anisotropy.

By directly linking Mg2+-dependent structural compaction to microsecond-scale dynamics, this work reveals fundamental physical principles governing the behavior of recombination intermediates at the single-molecule level.

Chanchal Sharma, A. K. Upadhyaya, D. Sasmal · 0 citations
Review Open access Jul 2026

Curving Actin Across Systems: Do Axonal Actin Rings Share Common Underlying Mechanisms?

Actin polymerization into curved and ring‐shaped structures is an evolutionarily conserved mechanism that cells use to generate force, transmit tension, and maintain membrane architecture. In neurons, super‐resolution imaging has revealed a striking periodic submembranous scaffold in axons, composed of circumferential...

A. R. Costa, Luís P. Rodrigues, Monica M. Sousa · 0 citations
Open access Aug 2026

Molecular orchestration of global actin remodelling by INF2

The findings uncover a novel product-inhibition mechanism that limits INF2 function and offer important insight into disease mechanisms linked to actin dysregulation.

Felix Uecker, Sven Wargenau, Micaela Boiero Sanders et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.