Impact of 18 Months of Magnetoencephalography-Magnetic Source Imaging on Presurgical Decision-Making for Epilepsy Surgery in South Korea: A Single Pediatric Epilepsy Center Study
Jul 2026· Annals of Child Neurology· 0 citations· 19 references
TL;DR
Since MEG was incorporated into routine presurgical evaluation for patients with epilepsy, MEG-MSI findings have influenced clinical decision-making in 11 patients, supporting the clinical decision to proceed with resective surgery.
Abstract
Purpose: This study evaluated the impact of magnetoencephalography-magnetic source imaging (MEG-MSI) on the presurgical evaluation of patients with epilepsy. Methods: We retrospectively analyzed presurgical evaluation reports for 64 patients considered for epilepsy surgery at a single pediatric epilepsy center. Results: Overall, 52 of 64 patients (81%) were considered candidates for resective surgery before MEG-MSI. In 37 of these 52 patients (71%), MEG-MSI findings were concordant with those of other modalities, supporting the clinical decision to proceed with resective surgery. However, in 11 of the 52 cases (21%), resective surgery was no longer considered beneficial after MEG-MSI. Among these 11 patients, five underwent either corpus callosotomy or vagus nerve stimulator insertion. Conclusion: Since MEG was incorporated into routine presurgical evaluation for patients with epilepsy, MEG-MSI findings have influenced clinical decision-making in 11 patients.
The findings support incorporating detailed analysis of MEG cluster characteristics into presurgical evaluation to refine EZ localization, especially for invasive evaluation.
Ryuzaburo Kochi, Spencer Morris, I. Bluemcke et al.· Epilepsia· 0 citations
Purpose: This study evaluated surgical outcomes after stereoelectroencephalography (SEE-G)-guided epilepsy surgery in pediatric patients with drug-resistant epilepsy (DRE) compared with outcomes after conventional subdural grid evaluation. Methods: We retrospectively analyzed pediatric patients with DRE who underwent r...
Shi-Liang Jang, Hui-Jin Shin, Se Hee Kim et al.· Annals of Child Neurology· 0 citations
MRI volumetric assessment is a valuable adjunct to conventional MRI for detecting subtle hippocampal and hippocampal subfield volume loss in children with epilepsy, including those with normal conventional MRI findings.
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In a diagnostically heterogeneous real-world cohort, 1H-MRS significantly improved the accuracy achievable with conventional MRI alone and substantially increased reported diagnostic confidence, with high specificity but only moderate sensitivity.
L. Georgescu, Alexandru Șerbănoiu, A. Costache et al.· Diagnostics· 0 citations
Epilepsy is a neurological disorder affecting over 50 million people worldwide, with a global incidence of 7.6 per 1,000 individuals. Mesial temporal lobe epilepsy (MTLE) is characterized by recurrent, unprovoked seizures originating in the temporal lobe. The standard surgical treatment is anterior temporal lobectomy;...
V. A. García-García, Marco Vinicio Ramírez-Sánchez, R. García-Romero et al.· Chinese Neurosurgical Journa...· 0 citations
UHF T2*-weighted sequences may be useful to detect the black line sign and thereby refine surgical or ablation targeting for some FCDs and may improve diagnostic yield of 9.4-Tesla MRI.
Cornelius Kronlage, Pascal Martin, Benjamin Bender et al.· Epilepsia· 0 citations
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