Jul 2026· Photochemical and Photobiological Sciences· Vol 25, pp. 1839 - 1857· 0 citations· 39 references
Medicine
TL;DR
The determination and comparison of the MIC50 values of the selected TC compounds identified molecules exhibiting increased activity resulting from a conformational change under UVA exposure.
The present study suggests that photo-responsive polypeptide PNFs represent a promising and versatile therapeutic strategy for combating antibiotic-resistant bacterial infections, owing to their dual functional capabilities.
Sangita Rajwar, C. Kumar, Shreya Ghosh et al.· ACS Applied Bio Materials· 0 citations
This study aims to explore the antimicrobial photodynamic activity of hypericin (a naturally occurring non-toxic photosensitizer [PS]) and methylene blue (a chemical PS), which in combination with light can generate reactive oxygen species, thus effectively destroying the bacterial cells.
S. Alam, Ferdousi Akhter, E. Toma et al.· American Journal of Biopharm...· 0 citations
This work is the first to report the preparation of an azithromycin-loaded PHB–PEG delivery system for use against Salmonella, which provides a new drug-polymer formulation to be tested for its antimicrobial potential.
Z. Hamasadek, K. Aziz, Payman A. Kareem· passer of basic and applied...· 0 citations
HA and PM substantially enhanced the antibacterial performance of OCT and PHMB under photodynamic activation, enabling complete S. aureus inactivation, and highlight PS-antiseptic combinations as a promising non-antibiotic strategy for chronic wound management while reducing the required PS and antiseptic concentration...
Lília S. Teixeira, Sónia Fraga, Manuel Simões et al.· Journal of materials chemist...· 0 citations
Ruthenium-based photosensitisers appear to act predominantly through singlet oxygen-mediated oxidative stress, enhancing cefotaxime efficacy while exhibiting low cytotoxicity, and therefore represent promising adjunct therapies against MDR K. pneumoniae.
M. F. Cuevas, Scarlet Vallejos-Monroy, Valentina A. Iglesias et al.· British Journal of Pharmacol...· 0 citations
It is demonstrated that small ligand modifications can cause strongly differentiated aPDT-relevant behaviour and that silica-immobilised Cu(i) photosensitisers offer a promising option for light-mediated surface disinfection/sanitation applications.
Alexander Dukalski, Çağrı Özsan, Florian Doettinger et al.· Dalton Transactions· 0 citations
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