Overall, S. cavourensis BA1 represents a promising source of antibacterial metabolites, although genome sequencing, bioassay-guided purification, and mechanistic studies are required to confirm the active principles and therapeutic safety in vivo.
Findings highlight S. enissocaesilis ASB as a promising source of extracellular bioactive metabolites and provide a foundation for future studies involving compound purification, structural characterization, safety evaluation, and translational development against MDROs.
A. Badawy, E. M. El-Fakharany, Jehan S. Albrahim et al.· Biologia· 0 citations
The integrated experimental and in silico approach highlights soil-derived actinomycetes as versatile and sustainable bioresources with significant pharmaceutical and biotechnological potential, emphasizing their role in combating antimicrobial resistance and enabling the rational development of novel therapeutic and i...
Meghana Arivilu, S. Sulthana, Vijay Ramesh et al.· Journal of Pure and Applied...· 0 citations
Abstract The global rise in antibiotic resistance has increased the demand for new natural antibacterial agents derived from microorganisms. This study aimed to isolate and characterize antibacterial metabolites produced by the micromycete Trichoderma asperellum Uz-A4 The strain was cultivated under controlled conditio...
H. Karimov, A. Inkhonova, N. Azimova et al.· Brazilian Journal of Biology· 0 citations
Abstract The marine environment harbours a rich diversity of microorganisms capable of producing bioactive compounds, including pigments with significant therapeutic potential. However, the exploration of bacterial pigments from marine bacteria, particularly from Cox’s Bazar region in Bangladesh, remains under-research...
Ashrafunnesa Flora, Sadia Afrin, M. N. I. Bhuiyan et al.· Journal of the Marine Biolog...· 0 citations
The increasing prevalence of multidrug-resistant (MDR) Staphylococcus aureus represents a major challenge for global public health and highlights the urgent need for new antimicrobial strategies. In this context, plant-derived compounds have emerged as promising sources of bioactive molecules with antimicrobial and ant...
Beatriz Meyruze Barros da Fonsêca, V. Silva, Bruna de Sousa Gomes et al.· International Microbiology· 0 citations
Secondary metabolites are promising alternatives due to their diverse biological activities, including antimicrobial and antiviral effects. Wild plants, particularly Solanum elaeagnifolium Cav (Silverleaf Nightshade), harbor endophytic microorganisms that represent an untapped source of such bioactive compounds. In the...
Merihan S. Sabra, Lina Jamil M. Abdel-Hafez, Amr S. Bishr et al.· Frontiers in Cellular and In...· 0 citations
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