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#artificial intelligence Preprint Open access

Event-Aligned Analysis of Multi-Rater Pain Assessments Using Continuous Wearable Physiology

Saba A. Farahani Elahe Khatibi Thomas D. Hughes Ariana M. Nelson Hung Cao Amir M. Rahmani
Sep 2026
Artificial Intelligence

Abstract

Pain is assessed differently by patients, nurses, and clinicians, yet most computational approaches assume a single ground-truth label - effectively ignoring who is doing the rating. We introduce a rater-aware, event-aligned framework that converts sparse, rater-specific pain ratings into discrete pain-change events and aligns continuous wearable physiological signals to these events, preserving rater identity throughout. Applied to multimodal wearable data collected during spine-related pain procedures, the framework identifies substantial disagreement across rater groups and provides preliminary, exploratory evidence of rater-dependent physiological differences preceding reported pain increases. These findings suggest that pain-physiology relationships may not be rater-invariant, and that aggregating assessments across raters may mask meaningful physiological patterns. A rater-aware, event-aligned perspective is therefore a promising direction for interpreting wearable data in real-world clinical pain assessment.

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