Jul 2026· Cardiovascular Drugs and Therapy· 0 citations· 28 references
Medicine
TL;DR
circ_0089762 exacerbates H/R-induced apoptosis, oxidative stress, and inflammatory response in HUVECs by regulating miR-938 and STAT3 expression and may act as a potential biomarker for the diagnosis, prognostic assessment, and targeted treatment of AMI.
It is demonstrated that the downregulation of circ_0001112 promoted cardiomyocyte apoptosis by sponging miR-324-5p and upregulating CDK6 expression in MI.
Aizhen Hu, Lina Zhang, Xingping Men· Journal of biochemical and m...· 0 citations
Serum miR-369-3p may serve as a non-invasive diagnostic and prognostic biomarker for AIS and protects against ischemic endothelial injury by targeting VAV3 and mitigating inflammation and adhesion molecule expression.
Meijie Zhang, L. Yin, Zhixin Liu et al.· Neurochemical Research· 0 citations
It is indicated that HOTAIR aggravates hyperuricemia-induced endothelial injury by regulating the miR-141-3p/GPR75/NF-κB axis and provides new mechanistic insights into hyperuricemia-associated vascular dysfunction.
Jia-Wu Fu, Jun-Bing He, Ke-Shen Li et al.· Molecular Biology Reports· 0 citations
Background Acute myocardial infarction (AMI), characterized by acute myocardial necrosis due to coronary occlusion, is a life-threatening cardiovascular event. Ferroptosis critically contributes to ischemic injury, yet its causal regulators in AMI, particularly in endothelial cells, remain elusive. Methods We integrate...
Xiaona Yang, Zhong-Yan Li, Lingxiang Guo et al.· Frontiers in Pharmacology· 0 citations
Atherosclerosis (AS) is closely related to the pathogenesis and abnormal proliferation and migration of vascular smooth muscle cells (VSMCs). To explore the value of hsa_circ_0044097 in the clinical management of AS and to elucidate its role and mechanism in the injury of VSMCs induced by in vitro oxidized low‐density...
Cen-Cen Ren, Yun-Gen Jiao· Journal of biochemical and m...· 0 citations
To define the functional role of hsa_circ_0054391 (circ54391) in CRC progression and to evaluate its potential as a serum biomarker. Circ54391 was identified from databases and its expression was validated in CRC tissues, cell lines, and serum from healthy controls (
n
= 34), colorectal polyp patients (
n
= 3...
Cheng-Ying Xiong, Zhi-Qiang He, Xiao-Xue Liu et al.· Scientific Reports· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
