Aug 2026· Cancer Metastasis Review· Vol 45· 0 citations· 94 references
Medicine
TL;DR
A conceptual framework of how the dysfunction of the highly conserved NAT10 leads to tumorigenesis, metastasis, and therapeutic resistance is provided and the major findings that reveal how NAT10 regulates cancer metabolism and immune responses are summarized.
A comprehensive overview of the multifaceted functions of RNF5 is provided, with particular emphasis on its context-dependent roles in cancer progression, antiviral immunity, and non-neoplastic diseases.
Ruo-Bing He, Jiao Wang, Meng-Jia Lin et al.· Biochemical Pharmacology· 0 citations
This review systematically synthesizes current knowledge regarding the multifaceted roles of YTHDC2 in disease progression, prognosis, and therapy, offering a comprehensive framework to guide future investigations.
Yan-Ying Hu, Qi Zhou, Ning Xu et al.· Cells· 0 citations
Interferon-stimulated gene 15 (ISG15) encodes a ubiquitin-like protein that regulates diverse cellular responses, including antiviral immunity, through its conjugation to proteins in a process known as ISGylation. Several pathogens, including SARS-CoV-2, subvert ISGylation by encoding deISGylating enzymes. However, the...
The m6A regulatory system, the biological characteristics of major ncRNA classes, and the mechanisms through which m6A and ncRNAs interact in cancer are summarized.
Nan Li, Jia-Xue Lu, Wen-Ling Zhang· International Immunopharmaco...· 0 citations
This review systematically dissects how dysregulated m6A methylation fuels malignant transformation and progression by reinforcing core oncogenic hallmarks, sustained proliferation, metastasis, metabolic rewiring, and resistance to programmed cell death.
Sheng-Jie Tang, Rangping Xie, Jiang Fu et al.· Molecular Cancer· 0 citations
It is argued that while epitranscriptomics represents a compelling regulatory axis in cancer cell death, advancing the field will require integrative, high-resolution, and functionally precise approaches to move beyond correlative frameworks toward mechanistic and clinically actionable insights.
A. Mukherjee, Ankit Kumar Bharti, D. Mathew et al.· Functional & Integrative Gen...· 0 citations
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