2026· Methods in molecular biology· Vol 2999, pp.
425-449
· 0 citations
Medicine
TL;DR
This chapter provides a comprehensive and up-to-date review of PC, covering key aspects such as its epidemiology, aetiology and associated risk factors and evaluates the current paradigm of detection and treatment protocols.
The synthesis of data from mouse models and human-derived materials supports a speculative model where the crosstalk between BC cells and the microenvironment defines the metastasis pattern in carriers of GPVs in BCSGs.
I. Elkholi, W. Foulkes· Cancer Research· 0 citations
This narrative review aims to present the major hereditary cancer syndromes associated with an increased breast cancer risk, and to highlight the evidence-based genotype-specific screening and treatment protocols.
D. Pușcașu, Lavinia Caba, B. Gafton et al.· Oncology Research· 0 citations
This manuscript serves three purposes: a narrative review of recent systems genetics applications in EOCRC research, a step‐by‐step protocol for conducting these analyses, and a discussion of current advances in systems genetics to address limitations in generalizability and context dependence.
Minjae J. Kim, Sydney L. Carr, Vishnutheert Kulkarni et al.· Chemical Biology and Drug De...· 0 citations
Evidence shows that the interaction between genetic predisposition and environmental factors is a key determinant of breast carcinogenesis, underscoring the importance of understanding the underlying molecular mechanisms to improve prevention and care strategies.
Ana Paula Borges da Silva, Taynara de Almeida Campos, Juliano Rodrigues Coimbra et al.· Brazilian Journal of Health...· 0 citations
Current evidence on early-onset colorectal cancer epidemiology, biology, clinical presentation, screening, and treatment is summarized, and emerging directions including liquid biopsy, artificial intelligence, and microbiome-based strategies are highlighted.
Ahmed Sohaib, Ashwaq Salami, Wesal Alghwyeen et al.· Integrated Oncology Diagnost...· 0 citations
A more comprehensive understanding of the interactions between infection, chronic inflammation, and PCa development may facilitate the identification of novel biomarkers and therapeutic targets and contribute to improved risk stratification, earlier detection, and more effective treatment of PCa.
Ensiyeh Bahadoran, Abouzar Babaei, shahla shahbazi et al.· BioMed Research Internationa...· 0 citations
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