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Review Open access Sep 2026

Use of Nanotechnology in the Treatment of Periodontitis and Peri-Implantitis: A Narrative Review.

Nanotechnology has gained increasing attention as a promising approach for the management of periodontitis and peri-implantitis, providing innovative strategies for targeted drug delivery, antimicrobial action, and tissue regeneration. Nanostructured materials and nanocomposites have been developed to transport therape...

Valentino Natoli, Deepti Shrivastava, K. Srivastava · 0 citations
Review Sep 2026

Applications of hydrogels in periodontal tissue regeneration: From material design to clinical translation.

Periodontitis is a globally prevalent chronic infectious inflammatory disease that destroys periodontal supporting tissues and threatens systemic health. This review summarizes hydrogel-related research for periodontal tissue regeneration and explores its synergistic application value with conventional therapies. We co...

Ying-Jie Sun, Xian-Bin Zeng, Wen-Ting Zhang et al. · 0 citations
Review Open access Sep 2026

Melatonin-Hydrogel Delivery Systems for Effective Treatments of Periodontitis: Translational Perspectives from Material Designs to Clinical Applications

Periodontitis is a chronic infectious disease characterized by progressive destruction of periodontal supporting tissues. Conventional treatments, including mechanical therapy and local drug delivery, are hindered by poor drug retention, burst release, and short duration of action. Melatonin (MT), an endogenous indolea...

Ting Liu, Li Zhang, Qiong Zhang et al. · 0 citations
Open access Sep 2026

Graphene oxide-engineered dental implants: orchestrating antibacterial defense and osteo-immunomodulation for enhanced osseointegration

Dental implant technology has brought significant benefits to millions of patients with missing teeth, substantially improving their quality of life. However, titanium-based dental implants still face two stubborn problems—peri-implant infection and inadequate osseointegration, which seriously undermine their therapeut...

Qing-Fan Li, Yun Wang, Jia-Hui Hu et al. · 0 citations

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