It is established that ICEs are pervasive contributors to Pg’s pangenome and unique strain-level gene repertoires, and suggest that ICEs likely impact the virulence and ecology of Pg through the introduction and spread of advantageous traits.
ABSTRACT The rapid expansion of cervid farming raises concerns about antimicrobial resistance (AMR) dissemination, yet its impact on the Cervidae gut microbiome remains poorly characterized. We integrated 89 newly sequenced fecal metagenomes with 599 publicly available datasets, comprising 285 metagenomes from farmed c...
Yu-Zhe Sun, Jin-Wen Su, Hany M. Elsheikha et al.· Virulence· 1 citation
The gut virome is profoundly altered in inflammatory bowel disease (IBD), though phage evolution during inflammation remains poorly understood. We used viral tagging (VT) to recover phages of Phocaeicola vulgatus, a gut-associated pathobiont, from healthy and Crohn’s disease (CD) viromes, revealing phages related to th...
Megan T. Baldridge, Danielle E. Campbell, Xiao-Fen Wu et al.· Research Square· 0 citations
Advances in the understanding of toxin diversity and plasmid biology in C. perfringens are reviewed, highlighting the remarkable plasticity of its mobile genome and positioning C. perfringens as a compelling model to understand how mobile genetic elements drive virulence, adaptation and disease in bacterial pathogens.
Sarah A. Revitt-Mills, D. Lyras· Microbiology Australia· 1 citation
An open pan-genomic and functional analysis of 242 L. longbeachae isolates reveals an open pan-genome driven by extensive horizontal gene transfer and marked functional divergence between core and accessory genomes, revealing a distinct pathogenic profile in sg3 that differs from the canonical serogroups, characterized...
Jun-Wei Xu, Yuan He, Xue-Fu Zhou et al.· Applied and Environmental Mi...· 0 citations
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