Evaluation of high-fat diet-induced metabolic impairments in iBAT lipid metabolism using 1H-MRS.

A. Rengaraj G. T. Le Chandan Dharmashekar M. Leow H. Hu C. Shivamallu J. Eriksson S. S. Velan B. Ashokkumar J. Yaligar

Jul 2026 · MAGMA · 0 citations · 28 references

Medicine

TL;DR

HFD feeding caused insulin resistance and impaired iBAT mitochondrial functions and thermogenic activity, due to lipid accumulation, and chronic cold exposure improved insulin sensitivity and restored iBAT oxidative metabolism and mitochondrial functions.

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