The FA-loaded NIPAM-MAA nanogel effectively addresses the physicochemical limitations of fusidic acid, including poor solubility and rapid clearance, by providing a regulated and sustained release profile, however, formal cytocompatibility and in vivo efficacy evaluations are required before clinical translation.
The synthesis of polyolefin (PO) nanocomposites remains a significant challenge. This study reports the development of an injectable and in-situ curable elastomeric nanohybrid, synthesized from a functionalized polyalphaolefin resin (ACPAO) and methacrylate-modified chitosan (MACS) nanofiller. The PAO resin, a co-oligo...
Somayyeh Sadat Afi Kheljani, M. Nekoomanesh‐Haghighi, M. Atai et al.· International Journal of Bio...· 0 citations
Oxiconazole nitrate-loaded nanospheres were successfully developed using the emulsification–solvent evaporation method to enhance the solubility and dissolution of oxiconazole nitrate, a Biopharmaceutics Classification System (BCS) Class II antifungal drug characterized by low aqueous solubility and good membrane perme...
Suyash Shashikant Ingle, A. Chavan, Vasundhara Somnath Patil et al.· International Journal of Sci...· 0 citations
The emergence of antimicrobial resistance (AMR) necessitates the development of innovative delivery systems capable of maintaining enhanced therapeutic concentrations at the infection site. This study presents an innovative dual temperature and pH‐responsive nanogel system encapsulating poorly water‐soluble antibio...
Azizullah Mukhtar, Waqas Ahmad, Hassan Ali et al.· Journal of Applied Polymer S...· 0 citations
The present study was aimed at the formulation and characterizationof Rimegepant (RMG)-loaded polymeric nanoparticles (NP) for enhancedsolubility and oral delivery. RMG-loaded NP were prepared by thenanoprecipitation method using Eudragit RL100 as polymer and PVA asstabilizer. Preformulation studies confirmed the limit...
Rohit, T. Vijayakumari, R. N. Rao et al.· IJPAR JOURNAL· 0 citations
It is suggested that RST-loaded chitosan nanoparticles represent a promising oral nanocarrier system with sustained release characteristics and the potential to improve the oral performance of poorly water-soluble drugs such as rosuvastatin calcium.
M. Sarwer, R. M. Sarfraz, Asif Mahmood et al.· BioNanoScience· 0 citations
The successful incorporation of LEO into a nanosponge-based hydrogel and subsequent formulation as a hydrogel for targeted therapeutic applications are demonstrated and provide preliminary evidence supporting its potential therapeutic application.
Ram Narayanan Ravi, Maanvizhi Saba, A. Gnanamani· Journal of Pharmaceutical In...· 0 citations
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