H. C. Jha

From viral epigenetic reprogramming to neuroinflammation: Mechanisms driving neurodegeneration

Pharmacological targeting of bunyavirus-induced synaptic impairment prevents neuronal hyperexcitability

Orthobunyaviruses are linked to a broad spectrum of neurological disorders. However, the molecular determinants governing bunyavirus neuropathogenesis remain poorly understood, precluding the identification of drugs able to alleviate virus-induced neuronal dysfunctions. Here, we show that the prevalent, yet neglected,...

Introduction to alternative proteins.

Exploring the potential of Ayush-64 in mitigation of post-coronavirus disease of 2019 complications of Delta variant of severe acute respiratory syndrome coronavirus 2.

The results underscore Ayush-64's role in re-establishing immunometabolic balance and enhancing neural resilience, highlighting utilization of formulation against SARS-CoV-2 viral infection.

Nanotechnology for sustainable agriculture: advances, applications and emerging role of multiomics

Microglia in Alzheimer's disease: Insights into disease progression and therapy.

This chapter provides a comprehensive synthesis of microglial biology across multiple interfaces, including transcriptomic, lipid-associated metabolic, cell senescence, and metabolic reprogramming, and positions microglia biology as a metabolically plastic, spatially organized immune-regulated microenvironment that can...

From viral epigenetic reprogramming to neuroinflammation: Mechanisms driving neurodegeneration

This review highlights how neurotropic viruses co-opt epigenetic pathways to drive neurodegeneration and explores biomarker-driven strategies for personalized interventions in neurodegenerative disorders thus emphasizing potential epigenetic editing tools to restore neuronal homeostasis.