Aug 2026· Journal of Neurovirology· Vol 32· 0 citations· 76 references
Medicine
TL;DR
This review highlights how neurotropic viruses co-opt epigenetic pathways to drive neurodegeneration and explores biomarker-driven strategies for personalized interventions in neurodegenerative disorders thus emphasizing potential epigenetic editing tools to restore neuronal homeostasis.
This review will evaluate the most updated research evidence on the role of circRNAs in major neurodegenerative diseases and neurotropic viral infections and discuss future directions for identifying circRNAs-based biomarkers and developing circRNAs-targeted therapeutic strategies for age-related and virus-associated n...
Finley Medina, Anna Bellizzi· Journal of Neurovirology· 0 citations
The DNA damage response (DDR) network maintains genomic integrity, functions as a signaling hub that viruses exploit to drive pathogenesis, and constitutes a central interface between viral infection and host cell fate. This review discusses the molecular mechanisms by which viruses subvert host DDR pathways, with an e...
The results suggest that intracellular T. annulata and T. parva parasites could drive an immune evasion cancer hallmark in host lymphocytes by epigenetic silencing of genes for innate and adaptive immunity.
Marisol Giacomini, Aristeidis Panagiotou, Steve G. Odette et al.· PLoS Pathogens· 0 citations
This review summarizes the classification and epidemiological characteristics of major oncogenic viruses, as well as emerging viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and provides an integrated framework for understanding, preventing, and treating virus-associated tumorigenesis.
Persistent infection with high-risk human papillomavirus (HR-HPV) is the primary driver of cervical cancer; however, viral presence alone is insufficient to induce malignancy. The progression from initial infection to invasive carcinoma requires a coordinated series of alterations in both the viral genome and the host...
Anindita Kundu, B. Chaudhuri, P. Guchhait et al.· East African Scholars Journa...· 0 citations
The Epstein-Barr virus (EBV) has evolved complex mechanisms to manipulate the host immune system and epigenetic machinery, enabling it to establish lifelong latent infection within host cells. Emerging evidence strongly indicates that the EBV acts as a main epigenetic manipulator by silencing host regulatory genes, alt...
Sanaz Baghban Rahimi, Ahmad Hosseinzadeh Adli, Hossein Bannazadeh Baghi et al.· Clinical Epigenetics· 1 citation
Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.
