Author

I. Abramovich

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#protein folding Open access Oct 2026

HSP60 and HSP10 depletion provoke distinct biological responses

Abstract The mitochondrial chaperone and co-chaperone HSP60/HSP10 (HSPD1/ HSPE1), the mammalian homologues of bacterial GroEL/GroES, form a barrel-and-lid complex to fold newly imported or misfolded mitochondrial proteins. Several lines of evidence suggest that HSPD1 and HSPE1 have diverged in function. HSPD1 and HSPE1...

Hila Ben-David, Shani Gabbay, Sufa Sued-Hendrickson et al. · Philosophical transactions o... · 0 citations

Open access Aug 2026

Human gut microbiome as a composite health biomarker

ABSTRACT Using a cohort of 893 adults who underwent medical check-ups with rich data collection across diet, lifestyle, clinical labs, cardiac stress testing, and microbiome profiling, we show that a gut microbial health index (MHI), originally defined using a large meta-analysis of various human disease cohorts, is al...

T. Braun, Orli Harounian, R. Hadar et al. · Gut microbes · 0 citations