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Author

J. Hoogerwerf

3 papers indexed here

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Open access Sep 2026

Implications of different SOFA score variants for outcome prediction in emergency department patients with an infection: a multicenter cohort study.

BACKGROUND The Sequential Organ Failure Assessment (SOFA) score estimates mortality risk and ICU admission in Emergency Department (ED) patients with infection, but not all parameters are routinely available outside the ICU. Several adaptations have been proposed, yet their impact on prognostic performance remains uncl...

T. J. van der Aart, Carolina Hincapié-Osorno, Isaac Santiago Arango-Gil et al. · 0 citations

The role of CD44 and osteopontin in infection and inflammation

The data indicate that IRAK-M impairs host defense during pneumonia caused by two common respiratory pathogens, including Klebsiella pneumonia and Streptococcus pneumonia.

J. Hoogerwerf, D. Blok, Alex et al. · 0 citations

The role of CD44 and osteopontin in infection and inflammation

OPN levels are rapidly increased in the bronchoalveolar space during K. pneumoniae pneumonia, where OPN serves a chemotactic function towards neutrophils, thereby facilitating an effective innate immune response.

J. Hoogerwerf, Sandrine · 0 citations

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