Abstract Platelet lysate (PL), enriched with growth factors, cytokines, and proteins, exhibits strong regenerative potential, positioning it as a promising bioactive agent in tissue engineering (TE). This review systematically summarizes the research progress, applications, and mechanisms of PL-loaded biomaterials in T...
Zhi-Kui Huo, Qian-Chuang Sun, Jin-Bao Xiao et al.· International Journal of Nan...· 0 citations
Distraction osteogenesis (DO) remains limited by prolonged consolidation and delayed bone union. This study evaluated whether a biodegradable, bone morphogenetic protein-2 (BMP-2)-releasing intramedullary implant (IMI) could enhance bone regenerate formation in a rat monofocal femoral lengthening model. We developed a...
Tomohiro Uno, Tien-Ching Lee, Krish Shah et al.· Acta Biomaterialia· 0 citations
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