Author

Ju-Mi A. Shin

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2026

Targeted Transition Mutations in Phage-Assisted Evolution.

This work integrated the MutaT7 system, which uses two base deaminases, into phage-assisted evolution to direct all four transition mutations specifically to the GOI, promoting the accumulation of all transition mutations, providing greater diversification of the GOI.

Thandava Vanapilli Nursimulu, Maryam Ali, Ju-Mi A. Shin · Methods in molecular biology · 0 citations

Review Open access Aug 2026

Exploring the Evolutionary Landscape with Targeted In Vivo Hypermutations

In this review, a review of recent in vivo hypermutation tools that enable rapid sampling of the vast evolutionary landscape, all while supporting simultaneous selection of the best proteins within living organisms are discussed.

Thandava Vanapilli Nursimulu, Maryam Ali, Ju-Mi A. Shin · Biomedicines · 0 citations