Open access
Jul 2026
CD4-directed nanoblades enable selective genome editing in CD4+ cells and HIV suppression in vitro and in vivo
A proof-of-concept study supports the promise of CD4-NBs as a minimally invasive, CD4⁺ cell-targeted gene editing strategy for HIV therapy and reduces viremia in ART-pretreated humanized mice.
Jolien Van Cleemput, Maaike De Cock, R. Verbeek et al.
· EMBO Molecular Medicine · 0 citations