Well-characterized iPSC reference panels are critical for developmental and disease-modeling research. We generated eleven iPSC clones from fibroblasts collected from four healthy, unrelated donors (two female, two male) using non-integrating Sendai virus reprogramming. Each clone was extensively validated according to...
Ellen Mosca, E. Stein, Jiss John et al.· Stem Cell Research· 0 citations
High-quality, standardized iPSC reference lines are crucial for disease modeling and regenerative medicine. We generated and extensively characterized thirteen iPSC clones from PBMCs of five healthy donors (three female, two male) using non-integrating Sendai virus. This resource is distinguished by its standardized de...
E. Stein, Ellen Mosca, Jiss John et al.· Stem Cell Research· 0 citations
Transposable elements are abundant in host genomes but are generally considered to be confined to the cell in which they are expressed, with the notable exception of endogenous retroviruses. Here, we identify a group of long terminal repeat (LTR) retrotransposons that infect the germline from somatic cells within the D...
Maya Voichek, A. Bernhard, Lea Lauterjung et al.· Cell· 1 citation
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