HSP60 and HSP10 depletion provoke distinct biological responses
Abstract The mitochondrial chaperone and co-chaperone HSP60/HSP10 (HSPD1/ HSPE1), the mammalian homologues of bacterial GroEL/GroES, form a barrel-and-lid complex to fold newly imported or misfolded mitochondrial proteins. Several lines of evidence suggest that HSPD1 and HSPE1 have diverged in function. HSPD1 and HSPE1...
Hila Ben-David, Shani Gabbay, Sufa Sued-Hendrickson et al.
· Philosophical transactions o... · 0 citations