Author

Qian Cai

3 papers indexed here

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Open access Nov 2026

Atractylenolide II Alleviates 5-Fluorouracil-Induced Intestinal Toxicity Through Potentially Targeting the TLR4-Mediated MYD88/NF-κB Signaling Pathway: An Integrated In Silico and In Vitro Study

5-Fluorouracil (5-FU) is a potent compound in anti-tumor chemotherapy; however, its clinical utility is hampered by dose-limiting intestinal toxicity. Atractylenolide II (AT-II), a bioactive sesquiterpene derived from Atractylodis Rhizoma, has reported anti-inflammatory and cytoprotective activities. In this study, we...

Yang-Zhi Liu, Ru Jia, Yue Liu et al. · Molecules · 0 citations

#protein folding Open access Nov 2026

Self-Assembled Particles from Raw and Bran-Fried Atractylodes lancea Exert Spleen-Strengthening Effects via TFF1/NF-κB Pathway and Gut Microbiota Remodeling

It was revealed that the self-assembled particles reversed SDS-induced gut dysbiosis, characterized by increased abundance of beneficial Dubosiella and decreased abundance of pathogenic Escherichia-Shigella and downregulated TFF1/NF-κB p65 protein expression.

Ming-Yang Cui, Xing-Yi Li, Yang Qu et al. · Pharmaceuticals · 0 citations

Open access Oct 2026

SaCas9-Mediated CrtYB Disruption Coupled with Heterologous α-Bisabolol Production in Rhodotorula mucilaginosa JY1105

Rhodotorula mucilaginosa is a promising host for terpene biosynthesis, but its rational engineering remains constrained by limited genome-editing tools. Here, we developed a Staphylococcus aureus Cas9 (SaCas9) workflow in R. mucilaginosa JY1105 for CrtYB disruption and demonstrated heterologous α-bisabolol production....

Wen-Yi Sun, Hao-Yang Liu, Ya-Qi Dong et al. · Microorganisms · 0 citations