Large language models (LLMs) are increasingly involved in scientific discovery, yet it remains unclear whether they can support complex real laboratory science. Here we introduce Science Edge Evaluation (SEE), a multimodal benchmark of expert-curated questions grounded in peer-reviewed literature and experimental practice in chemistry, biology, and materials science. Evaluation of 19 multimodal large language models (MLLMs) shows that even the best-performing model reaches only 48.7% accuracy. Moreover, general-purpose models outperform science-specialized models on average. In the visual-agent evaluation, the use of tools increases the best accuracy to 52.7%. Tool use can expand the information available to models, but more information does not necessarily lead to reliable scientific reasoning. The key challenge is whether models can manage tool-derived information within the boundaries of the original experimental evidence. Together, these findings reveal that current MLLMs still cannot reliably make justified and evidence-bounded inferences from experimental results, which is an essential capability in real scientific discovery. Bridging this gap requires MLLMs to transition from explaining established scientific concepts to deriving novel and evidence-based insights from experimental data.
Tao Han, Yucheng Zhang, Jinghang Wang et al.· 0 citations
Native computer use offers a general interface for agents to operate almost any software available to people, but requires long-horizon state tracking, large-scale interactive experience, and learning from sparse yet verifiable outcomes. We introduce Qwen-CUA, a native computer-use agent with a 397B-A17B Qwen mixture-of-experts backbone. It observes only screenshots and acts through keyboard and mouse events, without DOM trees, accessibility metadata, or task-specific APIs. Its scaffold maintains up to 20 active screenshots and folds older visual history in fixed-size blocks to retain recent evidence while preserving reusable prompt prefixes. For training, we build a cloud rollout fleet with access to nearly 100,000 vCPUs and tens of thousands of concurrent environments, construct approximately 40,000 verifiable tasks, and collect personalized long-horizon workflows across everyday and professional software. We optimize complete trajectories with verifiable rewards and trajectory slicing, while iterative training runs refresh supervised data and recalibrate reinforcement-learning tasks. Across eight benchmarks, Qwen-CUA outperforms Qwen3.7 and remains competitive with leading proprietary systems, reaching 86.2 on OSWorld-Verified and 18.5/48.4 binary/partial completion on OSWorld 2.0. Scaling the same recipe to a model with over one trillion parameters yields Qwen-CUA-Max, improving these scores to 87.6 and 21.2/53.3. Qwen-CUA also reduces RedTeamCUA attack success from 36.6 to 16.4 relative to Qwen3.7. Efficiency analyses, a browser deployment, and Bash-augmented experiments further characterize practical behavior. These results establish native computer use as a broadly capable agent foundation and highlight scalable verifiable interaction and hybrid tool use as key directions.
Dunjie Lu, Shuai Bai, Tianyi Bai et al.· 0 citations