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Author

T. J. Buckley

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Review Sep 2026

Gene regulatory mechanisms downstream of DNA methylation.

How specialized reader proteins and transcription factors interpret DNA methylation to preserve methylation patterns, recruit effector complexes, regulate chromatin accessibility and interact with parallel epigenetic systems to mediate transcriptional silencing and activation across mammals and plants is reviewed.

T. J. Buckley, Mannix J. Burns, Lucas Jarry et al. · 0 citations
#gene editing Open access Aug 2026

Chromatin-Assisted Targeting Enables Precise DNA Methylation Editing in Plants

SunTag-NOVA robustly installed DNA methylation and repressed transcription at the endogenous FWA, FT and TMM genes with minimal genome-wide off-target consequences, and establishes SunTag-NOVA as a specific epigenome-editing platform for plants.

Yan He, Ming Wang, T. J. Buckley et al. · 0 citations

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