Author

Ute Krengel

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#protein folding Open access Sep 2026

A Single Amino Acid in the A2 Linker of Cholera Toxin Affects the Efficiency of Toxin Disassembly and Resulting Toxicity

The collective data uncover the critical role of D229 in toxin folding and structural dynamics, which in turn impacts toxin potency through effects on the efficiency of PDI-driven toxin disassembly.

F. Kersten, Natalia Mojica, Albert Serrano et al. · ACS Omega · 0 citations

Review Aug 2026

Conserved copper(I)-binding auxiliary domains link virulence-associated LPMOs to copper homeostasis in the intestinal environment

It is demonstrated that these multidomain LPMOs from food-borne intestinal disease-causing Gram-positive bacteria from the genera Bacillus and Listeria contain conserved, yet structurally distinct copper(I)-binding motifs on their non-catalytic third domain.

Eirik G. Kommedal, Hanne Berggreen, Synnøve Elisa Rønnekleiv et al. · bioRxiv · 0 citations